Specific effects of bortezomib against experimental malignant pleural effusion: a preclinical study

Please use this identifier to cite or link to this item: http://hdl.handle.net/10889/4833

Title:	Specific effects of bortezomib against experimental malignant pleural effusion: a preclinical study
Authors:	Psallidas, Ioannis Karabela, Sophia P Moschos, Charalampos Sherrill, Taylor P Kollintza, Androniki Magkouta, Sophia Theodoropoulou, Panagiota Roussos, Charis Blackwell, Timothy S Kalomenidis, Ioannis Stathopoulos, Georgios T
Issue Date:	2011-12-02
Keywords:	Lewis lung carcinoma Malignant pleural effusions
Keywords (translated):	Καρκίνωμα του πνεύμονα Κακοήθης Πλευριτική Συλλογή
Source:	Molecular Cancer
Abstract:	-
Abstract (translated):	We have previously shown that nuclear factor (NF)-κB activation of mouse Lewis lung carcinoma (LLC) specifically promotes the induction of malignant pleural effusions (MPE) by these cells. In the present studies we hypothesized that treatment of immunocompetent mice with bortezomib tailored to inhibit cancer cell NF-κB activation and not proliferation specifically inhibits MPE formation by LLC cells.
Appears in Collections:	Τμήμα Ιατρικής (Δημοσ. Π.Π. σε περιοδικά)

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